PHENIX is a software suite for automated macromolecular structure determination that can rapidly arrive at an initial partial model of a structure without significant human intervention, given moderate resolution and good quality data. This has been made possible by the development of novel algorithms for structure determination, maximum-likelihood molecular replacement (PHASER), heavy-atom search (HySS), template and pattern-based automated model-building (RESOLVE), automated macromolecular refinement (phenix.refine), and iterative model-building, density modification and refinement that can operate at moderate resolution (RESOLVE, AutoBuild). These algorithms are based on a set of crystallographic libraries that have been built and made available to the community.

Licenses GNU Lesser General Public License 2.1
Categories Data analysis Crystallography Macromolecular Crystallography
Software Requirements -
Hardware Requirements -
Platforms Mac OS Linux Windows
Languages Python
Input Formats There are no input formats associated to this software.
Output Formats There are no output formats associated to this software.
Contact email

Installed on the central cluster (rnice) and runnable via:>phenix

Documentation / Tutorials

Documentation Tutorials


Acta Cryst. D66, 213-221, 2010) P. D. Adams, P. V. Afonine, G. Bunkóczi, V. B. Chen, I. W. Davis, N. Echols, J. J. Headd, L.-W. Hung, G. J. Kapral, R. W. Grosse-Kunstleve, A. J. McCoy, N. W. Moriarty, R. Oeffner, R. J. Read, D. C. Richardson, J. S. Richardson, T. C. Terwilliger and P. H. Zwart, "PHENIX: a comprehensive Python-based system for macromolecular structure solution."

Instruments ID23-1 (ESRF) ID23-2 (ESRF) ID29 (ESRF) ID30A-1 (ESRF) ID30A-3 (ESRF) ID30A-2 (ESRF) ID30B (ESRF)
This software is used at these institutes
No example datasets have been uploaded for this software.